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Zurko Research Joins the Care of the Exposome via H&PC Today

REDEFINING THE ANTI-AGING CONCEPT: TREATMENT OR PREVENTION?

Several internal factors affect our appearance and natural aging process (mainly genetic factors) in our skin. It should be noted, that recent scientific publications establish a genetic association between the MC1R gene and the age shown in your face.

The MC1R gene codifies a protein which alters the melanocortin receptor, and intervenes in the pigmentation of the skin and hair. This is why recent studies have found that for example redhead people tend to appear up to two years younger.

At the same time, there is a strong correlation between certain external factors and how they act by modifying, in positive and in negative, the age of our skin. For example, we can highlight factors such as the intense and prolonged (over time) sunlight exposure, which moves forward the biological clock of our skin an average of four years.   Talking about tobacco consumption, it ages our skin on average in two years more. On the other hand, a healthy hydrated skin, as well as a good oral hygiene appearance can make us look two years younger.

There are 7 principal external factors that affects our genome (solar radiation, pollution, temperature, nutrition, stress, lack of sleep and cosmetics use). When these factors alter our appearance and our biological clock is known as EXPOSOME.

Regarding solar radiation, several studies have shown that either visible light as UV radiation impact our skin. Both induce the degradation of the dermal matrix, modify the lipid composition of the outermost layer of the epidermis and modulate the pigmentation of the skin.

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